Reliv Lunarich: Working directly at the Epigenetic Level

This product optimizes bioactive lunasin – a naturally occurring soy peptide and the first nutritional compound identified to work directly at the epigenetic level by increasing expression of certain genes, to help promote optimal cell health. While many other dietary compounds are known to affect gene expression, their exact mechanisms of action (how they work) remain unknown.

The Revolutionary Skincare Solution: AgeLOC Me

This revolutionary skin care experience was developed using the same science technologies used to create Y-span, except it is targeted at the outside of our bodies (i.e. our skin) rather than the inside. The science used to develop AgeLOC Me incorporates one of core concepts of Epigenetics – by gaining a more precise understanding of how the nutrients and antioxidants that we topically apply to our skin can influence the way our genes express themselves, to ultimately have a positive effect on our skins health and ageing process. However, another critical element is incorporated into the scientific design of this skin care solution – it is customized to your own personal environment!

The Revolutionary Supplement: Y-span

The science behind the development of products such as Y-span was based on one of the core concepts of Epigenetics – by gaining a more precise understanding of how the nutrients and antioxidants that we consume in our diet (which is an important part of our lifestyle and environment) can influence the way our genes express themselves, to ultimately have a positive effect on our health, wellbeing and ageing process.

So first things first – how do we know which genes we want to study? A proprietary gene expression on ageing (a database that shows how our gene expression changes as we age) was used to elucidate specific sets of genes that are involved in the ageing process – they have been termed Youth Gene Clusters. These Youth Gene Clusters are involved in enabling our aging defense mechanisms to optimally function, thus helping to preserve our youth and fight off the onslaughts of aging.

So now that we know which genes we want to look at, how can we study the behaviour of these specific genes hidden deep within our cells? Well that’s where the science called Gene Expression Profiling comes into play. Gene Expression profiling uses a piece of technology called a DNA microarray or in more simpler terms a “gene chip”. In figure… you can see some “gene chips” (reference image), and these gene chips show us how certain target genes are expressing themselves (i.e. how much RNA is being produced from a gene), also termed “work output”. Green means low levels and red means high levels of gene expression (i.e. low and high levels of RNA being produced, respectively).

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The ageing process involves negative changes to our epigenome, and this is demonstrated by the fact that there is such significant differences seen between the gene expression patterns of the young and old cell. Going back to my Epigenetic symphony metaphor – The symphony that is being played by the instruments of the orchestra in this old cell is in discord and disharmony, and really would not sound very pleasant to listen to! The symphony that is played in the young cell is perfectly tuned and in harmony, and I think that everyone would pay for front row tickets to this show! I think it’s also safe to say that we would all like our genes to behave like they do in young cells, even if technically we are let’s say “chronologically advanced” (a more PC way of saying old!).

Not only does the gene expression profile captured by a gene chip allow us to compare old vs young cells, but it also tells us what the cell is doing at any certain time under any certain condition i.e. what happens before and after a specific nutrient is applied to the cell.

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Using all of this science and technology, a library of natural ingredients (i.e. nutrients and antioxidants already scientifically known for their health qualities) were screened to test their effects/changes on the expression profile of Youth Gene Clusters in old cells. Out of the vast library that was screened, the ingredients that were selected to create Y-span were those that worked in synergistic harmony to demonstrate the greatest positive impact in influencing the Youth Gene cluster expression profile in old cells to behave more like that which is seen in the same genes in the young cells.

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By now some of you may be thinking… Is it safe to influence the expression of our genes in this way? Well the ageLOC science behind Y-span is not gene therapy, genetic engineering or gene splicing – so there’s no risk of inadvertently becoming a mutant! All that is happening when you use such supplemental solutions as Y-span is that they are creating the scientifically researched optimal targeted nutrient environment in which to promote positive changes to our cells epigenome, and subsequently enable optimal healthy and youthful gene expression.

Every single day with every lifestyle choice that we make (whether it be positive or negative), our environment is influencing the expression of our genes . Epigenetics is a constant, fluid and malleable process and with solutions such as Y-span we can optimize this potential to the advantage of our health, wellness and aging process. Nutraceutical products created using gene expression technology such as Y-span do not replace a healthy lifestyle, but they can work in harmony with us and to allow us to be the optimal conductors of our own positive gene expression.